Molecular Therapy — Nucleic Acids · 2020 · 58 citations · 34 references
MedicineCancer BiologyOncologyGene ExpressionMolecular OncologyTumor ProgressionBladder CancerCancer BiomarkersMicrorna-mediated RegulationNext-generation Sequencing In OncologyNoncoding Rna In CancerTumor Suppressor GenesCircular Rna FunctionCircular RnasLuciferase Reporter AssaysLuciferase ReportersMicrorna Function In CancerMicrorna In CancerMicrorna Regulation In CancerWestern Blotting
. Moreover, the circRIMS1/miR-433-3p/CCAR1 regulatory axis was confirmed to be responsible for the biological functions of circRIMS1. Taken together, our research demonstrated that circRIMS1 promotes tumor growth, migration, and invasion through the miR-433-3p/CCAR1 regulatory axis, representing a potential therapeutic target and biomarker in bladder cancer.
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