Color lens-free imaging using multi-wavelength illumination based phase retrieval

Abstract

Accurate image reconstruction in color lens-free imaging has proven challenging. The color image reconstruction of a sample is impacted not only by how strongly the illumination intensity is absorbed at a given spectral range, but also by the lack of phase information recorded on the image sensor. We present a compact and cost-effective approach of addressing the need for phase retrieval to enable robust color image reconstruction in lens-free imaging. The amplitude images obtained at transparent wavelength bands are used to estimate the phase in highly absorbed wavelength bands. The accurate phase information, obtained through our iterative algorithm, removes the color artefacts due to twin-image noise in the reconstructed image and improves image reconstruction quality to allow accurate color reconstruction. This could enable the technique to be applied for imaging of stained pathology slides, an important tool in medical diagnostics.