Concepedia

P2X<sub>3</sub> Receptor in Primary Afferent Neurons Mediates the Relief of Visceral Hypersensitivity by Electroacupuncture in an Irritable Bowel Syndrome Rat Model

Fang Zhang, Zhe Ma, Zhijun Weng, Min Zhao, Handan Zheng, Luyi Wu, Yuan Lu, Chunhui Bao, Yanan Liu, Huirong Liu,

Gastroenterology Research and Practice · 2020 · 12 citations · 21 references

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Abstract

EA can regulate the P2X<sub>3</sub> receptor protein and mRNA expression levels in the colon and related DRG of IBS rats with visceral pain and then regulate the excitatory properties of DRG neurons.

References

21

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A-317491, a novel potent and selective non-nucleotide antagonist of P2X <sub>3</sub> and P2X <sub>2/3</sub> receptors, reduces chronic inflammatory and neuropathic pain in the rat

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Neuronal soma–satellite glial cell interactions in sensory ganglia and the participation of purinergic receptors

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