Gut · 2008 · 139 citations · 38 references
These data suggest that the large enhancement of P2XR expression and function may contribute to the maintenance of visceral hypersensitivity, thus identifying a specific neurobiological target for the treatment of chronic visceral hyperalgesia.
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A P2X purinoceptor expressed by a subset of sensory neurons
Chih‐Cheng Chen, Armen N. Akopian, Lucia G. Sivilotti et al. · Nature · 1995 · 1K citations