Interaction of bacterial metagenome and virome in patients with cirrhosis and hepatic encephalopathy

Abstract

Unlike bacteria, faecal phages are sparsely linked with cirrhosis characteristics and 90-day outcomes. Phage and bacterial linkages centred on urease-producing, ammonia-generating <i>Streptococcus</i> species were affected by disease progression and rifaximin therapy and were altered in patients who experienced 90-day hospitalisations.