Fast-Growing Alveolar Echinococcosis Following Lung Transplantation

Clarisse Dupont, Frédéric Grenouillet, Jean‐Yves Mabrut, Frédérique Gay, Florence Persat, Martine Wallon, Jean‐François Mornex, F. Philit, Damien Dupont

Pathogens · 2020 · 12 citations · 11 references

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Abstract

. Its natural history is characterized by a slow parasitic growth over several years. Increased incidence and shorter development delay have been reported in immune-compromised patients. We report the reactivation of aborted lesions within 12 months of lung transplantation leading to a fast-growing aggressive hepatic lesion. Timely identification of alveolar echninococcosis allowed prompt albendazole treatment and radical surgery leading to a favorable outcome 42 months after transplantation. However, close clinical, serological and radiological monitoring is required to rule out relapses in the long term. The pre-existence of aborted self-limited lesions of alveolar echinococcosis and the possibility for their atypical rapid growth in patients undergoing profound immunosuppression should be known by healthcare providers, even if working in non-endemic areas.

References

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