medRxiv · 2020 · 11 citations · 20 references
Veterinary MedicineInfectious DiseasesUrban HealthClinical EpidemiologyEpidemiologyInfectious Disease EpidemiologyDisease SpreadInfectious Disease DynamicsInpatient CareHealthcare Facility Transmission DynamicsIntensive Care Unit ExposureIntensive Care Unit MortalityIntensive Care Unit To Intensive Care Unit TransferPhysical DistancingRural Population HealthSpatial Epidemiology ModelingTransmission Dynamics In Hospitals
Abstract Background COVID-19 has the potential to disproportionately affect the rural, remote, and Indigenous populations who typically have a worse health status and live in substandard housing, often with overcrowding. Our aim is to investigate the potential effect of COVID-19 on intensive care unit (ICU) resources and mortality in northwestern Ontario. Methods This study was conducted in northwestern Ontario which has a population of 230,000. A set of differential equations were used to represent a modified Susceptible-Infectious-Recovered (SIR) model with urban and rural hospital resources (i.e., ICU and hospital beds). Rural patients requiring ICU care flowed into the urban ICU. Sensitivity analyses were used to investigate the effect of poorer health status (i.e., increased hospital admission, ICU admission, and mortality) and overcrowding (i.e., increased contact rate) in the rural population as compared to the urban population. Physical distancing within the urban population was modelled as a decreased contact rate. Results At the highest contact rate, the peak in daily active cases, ICU bed requirements and mortality was higher and occurred earlier than lower contact rates. The urban population with a lower contact rate and baseline health status had a lower predicted prevalence of active cases and lower mortality than the rural population. Interpretation An increased contact rate and worse health status in the rural population will likely increase the required ICU resources and mortality as compared to the urban population. Rural populations will likely be affected disproportionately more than urban populations.
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Clinical Characteristics of Coronavirus Disease 2019 in China
Wei‐jie Guan, Zhengyi Ni, Yu Hu et al. · New England Journal of Medicine · 2020 · 31.2K citations · Full text
Veterinary Medicine, Infectious Diseases, Internal Medicine +10
Xiaobo Yang, Yu Yuan, Jiqian Xu et al. · The Lancet Respiratory Medicine · 2020 · 10.7K citations · Full text