Concepedia

FTH1 Inhibits Ferroptosis Through Ferritinophagy in the 6-OHDA Model of Parkinson's Disease

Ye Tian, Juan Lü, Xiaoqian Hao, Hang Li, Guiyu Zhang, Xuelei Liu, Xinrong Li, Caiping Zhao, Weihong Kuang, Dongfeng Chen,

Neurotherapeutics · 2020 · 430 citations · 25 references

DOIFull text

Open access

Concepts

References

25

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

Scott J. Dixon, Kathryn M. Lemberg, Michael R. Lamprecht et al. · Cell · 2012 · 18.1K citations · Full text

, , +10

Autophagy promotes ferroptosis by degradation of ferritin

Wen‐Chi Hou, Yangchun Xie, Xinxin Song et al. · Autophagy · 2016 · 2.2K citations · Full text

, , +16

Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion

Mario Mauthe, Idil Orhon, Cecilia Rocchi et al. · Autophagy · 2018 · 2.1K citations · Full text

, , +17

Activation of the p62‐Keap1‐NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells

Xiaofang Sun, Zhanhui Ou, Ruochan Chen et al. · Hepatology · 2015 · 2K citations · Full text

, , +17

Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy

Joseph D. Mancias, Xiaoxu Wang, Steven P. Gygi et al. · Nature · 2014 · 2K citations · Full text

, , +8