Journal of Pharmacognosy and Phytochemistry · 2020 · 64 citations · 0 references
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PharmacyMedicinal ChemistryPharmacologyDrug DiscoveryStructure-activity RelationshipsSystems PharmacologyIn Vitro PharmacologyMedicinal Plant KnowledgeMedicinal PlantsNetwork PharmacologyStructure-activity Relationship AnalysisVirtual ScreeningAdme ProfilingHerbal Compound Network AnalysisHerbal Drug DiscoveryIn Vivo StudiesPharmacokinetic ScreeningPharmacological ProfilingPharmacological ScreeningTraditional Medicinal Knowledge
In modern years, conventional medicinal plants analysis have constantly increased multinationally because plants allow them to complement modern pharmacological approaches. As computer mechanics developed, in silico approaches like network analysis and screening been extensively utilized to enlighten pharmacological basis of the functions of traditional medicinal plants. In these approach, network pharmacology, insilico screening and pharmacokinetic screening can augment active compounds among the candidates and indicate mechanism of action of medicinal plants. The present focus on the use of insilico ADME tool called SwissADME for pharmacological and pharmacognostic profiling of Butea monosperma Lam. The results of these study can be further carried forward by researcher to investigate the in vitro and in vivo studies to reveal the pharmacological basis of traditional medicinal plants.