Concepedia

Genome‐wide association study reveals a novel locus for asthma with severe exacerbations in diverse populations

Esther Herrera‐Luis, Antonio Espuela‐Ortiz, Fabián Lorenzo-Díaz, Kevin L. Keys, Angel C. Y. Mak, Celeste Eng, Scott Huntsman, Jesús Villar, José Rodríguez‐Santana, Esteban G. Burchard,

Pediatric Allergy and Immunology · 2020 · 28 citations · 26 references

DOIFull text

Open access

Abstract

We identified a novel susceptibility locus for severe asthma exacerbations in Hispanic/Latino and African American youths with functional effects in gene expression and methylation status of neighboring genes.

References

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Leveraging Polygenic Functional Enrichment to Improve GWAS Power

Gleb Kichaev, Gaurav Bhatia, Po‐Ru Loh et al. · The American Journal of Human Genetics · 2018 · 1K citations · Full text

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