Plasma Levels of Endothelial Cell Protein C Receptor Are Elevated in Patients With Sepsis and Systemic Lupus Erythematosus: Lack of Correlation With Thrombomodulin Suggests Involvement of Different Pathological Processes

Abstract

To the Editor: The endothelial protein C receptor (EPCR) is a recently described member of the protein C anticoagulant pathway.[1][1] [2][2] The membrane form of EPCR works in concert with thrombomodulin (TM) to augment protein C activation on endothelial cells,[3][3] whereas a soluble form of EPCR