Gene Therapy in Brain Tumours: Implications of the Size of Glioblastoma on its Curability

Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

Jay P. Morgenstern, Hartmut Land · Nucleic Acids Research · 1990 · 2.1K citations · Full text

Viral Replication, Engineering, Medicine +15

Improved retroviral vectors for gene transfer and expression.

A. Dusty Miller, G J Rosman · PubMed · 1989 · 2K citations · Full text

High-titer Virus Stocks, Viral Replication, Murine Retrovirus-based Vectors +14

In Vivo Gene Transfer with Retroviral Vector-Producer Cells for Treatment of Experimental Brain Tumors

Kenneth W. Culver, Zvi Ram, Stuart Wallbridge et al. · Science · 1992 · 1.5K citations

In Vivo Gene Therapy, Neural Stem Cell, Gene Delivery +18

The "bystander effect": tumor regression when a fraction of the tumor mass is genetically modified.

Sara M. Freeman, Camille N. Abboud, Katharine A. Whartenby et al. · PubMed · 1993 · 1.1K citations

Tumor Regression, Immunology, Viral Pathogenesis +23

Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: paradigm for a prospective cancer control strategy.

Frederick L. Moolten · PubMed · 1986 · 971 citations

Immunology, Cancer Biology, Tumor Biology +18