Concepedia

The BCL-2 family members NOXA and BIM mediate fluorizoline-induced apoptosis in multiple myeloma cells

Ana M. Cosialls, Ismael Sánchez‐Vera, Helena Pomares, Judit Perramon-Andújar, S. González Sánchez, Claudia Mariela Palmeri, Daniel Iglesias‐Serret, José Saura‐Esteller, Sonia Núñez‐Vázquez, Rodolfo Lavilla,

Biochemical Pharmacology · 2020 · 13 citations · 34 references

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34

Genome engineering using the CRISPR-Cas9 system

F. Ann Ran, Patrick D. Hsu, Jason Wright et al. · Nature Protocols · 2013 · 11.7K citations · Full text

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Antisense strategy shows that Mcl-1 rather than Bcl-2 or Bcl-xL is an essential survival protein of human myeloma cells

Sophie Derenne, Brett P. Monia, Nicholas M. Dean et al. · Blood · 2002 · 430 citations · Full text

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ERAD inhibitors integrate ER stress with an epigenetic mechanism to activate BH3-only protein NOXA in cancer cells

Qiuyan Wang, Helena Mora-Jensen, Marc A. Weniger et al. · Proceedings of the National Academy of Sciences · 2009 · 344 citations · Full text

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Proteasome Inhibitors Trigger NOXA-Mediated Apoptosis in Melanoma and Myeloma Cells

Jian‐Zhong Qin, Jeffrey Ziffra, Lawrence Stennett et al. · Cancer Research · 2005 · 338 citations

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Mcl-1 is overexpressed in multiple myeloma and associated with relapse and shorter survival

Soraya Wuillème‐Toumi, Nelly Robillard, P Gomez et al. · Leukemia · 2005 · 338 citations

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