Concepedia

Exploring the Molecular Mechanism of Cinnamic Acid-Mediated Cytotoxicity in Triple Negative MDA-MB-231 Breast Cancer Cells

Ambika Pal, Poulami Tapadar, Ranjana Pal

Anti-Cancer Agents in Medicinal Chemistry · 2020 · 29 citations · 49 references

DOI

Abstract

Thus, from the above observations, we can conclude that CA is an effective anticancer agent that can induce apoptosis in breast cancer cells via TNFA-TNFR1 mediated extrinsic apoptotic pathway.

References

49

Induction of TNF Receptor I-Mediated Apoptosis via Two Sequential Signaling Complexes

Olivier Micheau, Jürg Tschopp · Cell · 2003 · 2.6K citations · Full text

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Induction of Morphological and Biochemical Apoptosis following Prolonged Mitotic Blockage by Halichondrin B Macrocyclic Ketone Analog E7389

Galina Kuznetsov, Murray J. Towle, Hongsheng Cheng et al. · Cancer Research · 2004 · 265 citations

Targeting triple-negative breast cancer cells with the histone deacetylase inhibitor panobinostat

Chandra R. Tate, Lyndsay V. Rhodes, H. Chris Segar et al. · Breast Cancer Research · 2012 · 263 citations · Full text

Aqueous Cinnamon Extract (ACE-c) from the bark of Cinnamomum cassiacauses apoptosis in human cervical cancer cell line (SiHa) through loss of mitochondrial membrane potential

Soumya J. Koppikar, Amit Choudhari, Snehal Suryavanshi et al. · BMC Cancer · 2010 · 219 citations · Full text

Protective effects of cinnamic acid and cinnamic aldehyde on isoproterenol-induced acute myocardial ischemia in rats

Song Fan, Hua Li, Jiyuan Sun et al. · Journal of Ethnopharmacology · 2013 · 195 citations

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