Remdesivir triphosphate can efficiently inhibit the RNA-dependent RNA polymerase from various flaviviruses

Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses

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Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys

Travis K. Warren, Robert Jordan, Michael K. Lo et al. · Nature · 2016 · 1.6K citations · Full text

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Remdesivir is a direct-acting antiviral that inhibits RNA-dependent RNA polymerase from severe acute respiratory syndrome coronavirus 2 with high potency

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Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection

Emmie de Wit, Friederike Feldmann, Jacqueline Cronin et al. · Proceedings of the National Academy of Sciences · 2020 · 946 citations · Full text

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The antiviral compound remdesivir potently inhibits RNA-dependent RNA polymerase from Middle East respiratory syndrome coronavirus

Calvin J. Gordon, Egor P. Tchesnokov, Joy Y. Feng et al. · Journal of Biological Chemistry · 2020 · 890 citations · Full text

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