Concepedia

(Sub)micron particles forming in aqueous dispersions of amorphous solid dispersions of the poorly soluble drug ABT-199: A combined particle optical counting and field-flow fractionation study

Mette Sloth Bohsen, Philipp A. Elvang, Beate Reder-Hilz, Verena Lenz, Jörg Rosenberg, Martin Brandl

European Journal of Pharmaceutical Sciences · 2020 · 11 citations · 19 references

DOI

References

19

ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets

Andrew J. Souers, Erwin R. Boghaert, Scott Ackler et al. · Nature Medicine · 2013 · 2.9K citations

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Evaluation of Various Dissolution Media for Predicting In Vivo Performance of Class I and II Drugs

Eric Galia, Eleftheria Nicolaides, D. Hörter et al. · Pharmaceutical Research · 1998 · 915 citations

The use of amorphous solid dispersions: A formulation strategy to overcome poor solubility and dissolution rate

Guy Van den Mooter · Drug Discovery Today Technologies · 2011 · 550 citations

, , +9

Amorphous solid dispersion enhances permeation of poorly soluble ABT-102: True supersaturation vs. apparent solubility enhancement

Kerstin J. Frank, Karin M. Rosenblatt, Ulrich Westedt et al. · International Journal of Pharmaceutics · 2012 · 138 citations · Full text

, , +6

Formation of nano/micro-dispersions with improved dissolution properties upon dispersion of ritonavir melt extrudate in aqueous media

Ingunn Tho, Bernd Liepold, Joerg Rosenberg et al. · European Journal of Pharmaceutical Sciences · 2010 · 107 citations

, , +9