Suppression of PTTG1 inhibits cell angiogenesis, migration and invasion in glioma cells

Human glioblastoma arises from subventricular zone cells with low-level driver mutations

Joo Ho Lee, Young Seok Ju, Sung‐Hong Park et al. · Nature · 2018 · 645 citations · Full text

Medicine, Neuroscience, Oncology +16

Lomustine-temozolomide combination therapy versus standard temozolomide therapy in patients with newly diagnosed glioblastoma with methylated MGMT promoter (CeTeG/NOA–09): a randomised, open-label, phase 3 trial

Ulrich Herrlinger, Theophilos Tzaridis, Frederic Mack et al. · The Lancet · 2019 · 576 citations · Full text

Medicine, Oncology, Pharmacology +16

The long non-coding RNA PTTG3P promotes cell growth and metastasis via up-regulating PTTG1 and activating PI3K/AKT signaling in hepatocellular carcinoma

Jinlan Huang, Shunwang Cao, Qishui Ou et al. · Molecular Cancer · 2018 · 233 citations · Full text

Medicine, Molecular Biology, Oncology +17

Expression of pituitary-tumour transforming gene in colorectal tumours

Anthony P. Heaney, Regina Singson, Chris J. McCabe et al. · The Lancet · 2000 · 231 citations

Medicine, Molecular Biology, Oncology +12

Transforming growth factor-β1 induces epithelial-to-mesenchymal transition in human lung cancer cells via PI3K/Akt and MEK/Erk1/2 signaling pathways

Xiaofeng Chen, Huijun Zhang, Haibing Wang et al. · Molecular Biology Reports · 2011 · 129 citations

Life Sciences, Cell Biology, Oncology +16