Clinical Cosmetic and Investigational Dermatology · 2020 · 17 citations · 19 references
MedicineDermatologyImmunologyCosmetic DermatologyOcular ImmunologyPhotodermatologyInflammatory Skin DiseasesKeratinization DisordersPhotosensitivity DisordersSkin CareSun ProtectionSunburn PreventionDermatological PhotoprotectionFacial Sun ProtectionImmune Privilege InductionImmune Privilege MaintenanceImmunological MechanismsPhotoprotection In Pigmentary DisordersPhotoprotection MechanismsVitamin D Synthesis
Abstract: Sun protection has been recommended by public health authorities to reduce the risk of keratinocyte and melanocyte tumors, yet some sun exposure is required for vitamin D synthesis. Frontal fibrosing alopecia (FFA) is a cicatricial alopecia that has been reported to have an association with facial photoprotection. The brief review proposes the hypothesis that FFA arises as a result of excessive facial photo-protection with a resultant disturbance in immunological homeostasis mediated via the aryl hydrocarbon receptor-kynurenine pathway axis (AHR/KP) leading to the collapse of immune privilege at the hair bulge. Keywords: sun exposure, aryl hydrocarbon receptor, frontal fibrosing alopecia, 6-formylindolo [3, 2- b ]carbazole
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Vitamin D intake and incidence of multiple sclerosis
Kassandra L. Munger, S. M. Zhang, Éilis J. O’Reilly et al. · Neurology · 2004 · 1.1K citations
Regulatory T Cells in Skin Facilitate Epithelial Stem Cell Differentiation
Niwa Ali, Bahar Zirak, Robert Sanchez Rodriguez et al. · Cell · 2017 · 660 citations · Full text
Postmenopausal Frontal Fibrosing Alopecia
Steven Kossard · Archives of Dermatology · 1994 · 334 citations
Medicine, Dermatology, Pathology +13