Concepedia

Rapid Polysorbate 80 Degradation by Liver Carboxylesterase in a Monoclonal Antibody Formulated Drug Substance at Early Stage Development

Sisi Zhang, Hui Xiao, Rosalynn C. Molden, Haibo Qiu, Ning Li

Journal of Pharmaceutical Sciences · 2020 · 72 citations · 20 references

DOI

Concepts

References

20

Activity-based protein profiling: The serine hydrolases

Yongsheng Liu, Matthew P. Patricelli, Benjamin F. Cravatt · Proceedings of the National Academy of Sciences · 1999 · 1.1K citations

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1-Cys Peroxiredoxin, a Bifunctional Enzyme with Glutathione Peroxidase and Phospholipase A2 Activities

Jinwen Chen, Chandra Dodia, Sheldon I. Feinstein et al. · Journal of Biological Chemistry · 2000 · 453 citations · Full text

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Shaken, Not Stirred: Mechanical Stress Testing of an IgG1 Antibody

Sylvia Kiese, Astrid Papppenberger, Hanns‐Christian Mahler · Journal of Pharmaceutical Sciences · 2008 · 397 citations

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Degradation of Polysorbates 20 and 80: Studies on Thermal Autoxidation and Hydrolysis

Ravuri S. K. Kishore, Astrid Pappenberger, Isabelle Bauer Dauphin et al. · Journal of Pharmaceutical Sciences · 2010 · 282 citations · Full text

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Direct visualization of serine hydrolase activities in complex proteomes using fluorescent active site-directed probes

Matthew P. Patricelli, Dan K. Giang, Lisa M. Stamp et al. · PROTEOMICS · 2001 · 280 citations

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