Concepedia

Gout and pseudo-gout-related crystals promote GLUT1-mediated glycolysis that governs NLRP3 and interleukin-1β activation on macrophages

Félix Renaudin, Lucie Orliaguet, Florence Castelli, François Fenaille, Aurélie Prignon, Fawaz Alzaïd, Christèle Combes, Aurélie Delvaux, Yasmina Adimy, Martine Cohen‐Solal,

Annals of the Rheumatic Diseases · 2020 · 173 citations · 47 references

DOI

Concepts

References

47

The Inflammasome

Fabio Martinon, Kimberly Burns, Jürg Tschopp · Molecular Cell · 2002 · 6K citations · Full text

Gout-associated uric acid crystals activate the NALP3 inflammasome

Fabio Martinon, Virginie Pétrilli, Annick Mayor et al. · Nature · 2006 · 5.2K citations

, , +11

THE METABOLISM OF TUMORS IN THE BODY

Otto Warbürg, Franz Wind, Erwin Negelein · The Journal of General Physiology · 1927 · 4.4K citations · Full text

, , +17

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

Gillian M. Tannahill, Annie M. Curtis, Juraj Adamik et al. · Nature · 2013 · 4K citations · Full text

, , +12

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

Rongbin Zhou, Aubry Tardivel, Bernard Thorens et al. · Nature Immunology · 2009 · 2.7K citations

, , +12