Theranostics · 2020 · 128 citations · 47 references
MedicineCell BiologyOncologyMetastasisMolecular OncologyTumor MicroenvironmentCancer Cell SignalingCancer ProgressionCancer Stem CellsMetastatic Breast CancerTumor Microenvironment ModulationTumor-associated MacrophagesBreast Cancer Tumor MicroenvironmentCancer Cell MigrationCancer Metastasis MechanismsEpithelial-mesenchymal Transition In CancerEpithelial-mesenchymal Transition MarkersImmunosuppressive MicroenvironmentMetastasis PromotionTumor Microenvironment Regulation
Natural compound emodin suppresses EMT and CSC formation of breast cancer cells by blocking TGF-β1-mediated crosstalk between TAMs and breast cancer cells. Our study provides evidence suggesting that emodin harbors the potential for clinical development as a new effective and safe agent to halt metastatic recurrence of breast cancer.
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The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
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let-7 Regulates Self Renewal and Tumorigenicity of Breast Cancer Cells
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