Concepedia

Loss of SIRT4 promotes the self-renewal of Breast Cancer Stem Cells

Lutao Du, Xiaoyan Liu, Yidan Ren, Juan Li, Peilong Li, Qinlian Jiao, Peng Meng, Fang Wang, Yuli Wang, Yunshan Wang,

Theranostics · 2020 · 47 citations · 43 references

DOIFull text

Open access

Concepts

Abstract

These results demonstrate that SIRT4 exerts its tumor-suppressive activity via modulating SIRT1 expression in breast cancer and provide a novel cross-talk between mitochondrial and nuclear sirtuins.

References

43

Prospective identification of tumorigenic breast cancer cells

Muhammad Al‐Hajj, Max S. Wicha, Adalberto Benito‐Hernández et al. · Proceedings of the National Academy of Sciences · 2003 · 10.4K citations · Full text

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Isolation and <i>In vitro</i> Propagation of Tumorigenic Breast Cancer Cells with Stem/Progenitor Cell Properties

Dario Ponti, Aurora Costa, Nadia Zaffaroni et al. · Cancer Research · 2005 · 1.7K citations · Full text

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Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors

Jason I. Herschkowitz, Karl Simin, Victor Weigman et al. · Genome biology · 2007 · 1.3K citations · Full text

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Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease.

Chantale T. Guy, Marc Webster, Michael D. Schaller et al. · Proceedings of the National Academy of Sciences · 1992 · 1.2K citations

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Side Population Is Enriched in Tumorigenic, Stem-Like Cancer Cells, whereas ABCG2+ and ABCG2− Cancer Cells Are Similarly Tumorigenic

Lubna Patrawala, Tammy Calhoun, Robin Schneider‐Broussard et al. · Cancer Research · 2005 · 905 citations · Full text

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