Theranostics · 2020 · 91 citations · 0 references
Life SciencesMolecular BiologyMolecular MedicineCartilage RepairGene ExpressionInflammationCartilage DegenerationCartilage MetabolismJoint DiseaseMicrorna BiologyMicrorna-mediated RegulationOsteoarthritisCartilage Breakdown PathophysiologyDisease-associated MicrornasLuciferase ReportersQuantitative In Situ HybridizationRabbit ModelsRna ImmunoprecipitationSmad Signaling PathwayWestern Blot Analysis
Our study revealed an important role of CircCDK14/miR-125a-5p/Smad2 axis in OA progression and provided a potential molecular therapeutic strategy for the treatment of OA.