Weijie Chen

SARS-CoV-2 N protein promotes NLRP3 inflammasome activation to induce hyperinflammation

Pan Pan, Miaomiao Shen, Zhenyang Yu et al. · Nature Communications · 2021 · 518 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +17

STING promotes NLRP3 localization in ER and facilitates NLRP3 deubiquitination to activate the inflammasome upon HSV-1 infection

Wenbiao Wang, Dingwen Hu, Caifeng Wu et al. · PLoS Pathogens · 2020 · 237 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Effect of training-sample size and classification difficulty on the accuracy of genomic predictors

Vlad Popovici, Weijie Chen, Brandon D. Gallas et al. · Breast Cancer Research · 2010 · 231 citations · Full text

Medicine, Bioinformatics, Biostatistics +16

Pharmacological activation of AMPK prevents Drp1-mediated mitochondrial fission and alleviates endoplasmic reticulum stress-associated endothelial dysfunction

Jia Li, Yilei Wang, Yapu Wang et al. · Journal of Molecular and Cellular Cardiology · 2015 · 186 citations

Life Sciences, Cell Biology, Molecular Biology +14

Ginsenoside Rb1 and compound K improve insulin signaling and inhibit ER stress-associated NLRP3 inflammasome activation in adipose tissue

Weijie Chen, Junlian Wang, Yong Luo et al. · Journal of Ginseng Research · 2015 · 107 citations · Full text

Medicine, Endocrinology, Pharmacology +17