Network Pharmacology Analysis and Experiments Validation of the Inhibitory Effect of JianPi Fu Recipe on Colorectal Cancer LoVo Cells Metastasis and Growth

Abstract

Through effective network pharmacology analysis, we found that JPFR contains many effective compounds which may directly target cancer-associated signaling pathways. The <i>in vitro</i> and <i>in vivo</i> experiments further confirmed that JPFR could inhibit the growth and metastasis of CRC cells by regulating <i>β</i>-catenin signaling-associated genes or proteins.