GADL1 is a multifunctional decarboxylase with tissue-specific roles in β-alanine and carnosine production

Elaheh Mahootchi, Selina Cannon Homaei, Rune Kleppe, Ingeborg Winge, Tor‐Arne Hegvik, Roberto Pérez, Christian Totland, Floriana Mogavero, Anne Baumann, Jeffrey Glennon,

Science Advances · 2020 · 49 citations · 57 references

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Abstract

locus with plasma levels of carnosine, subjective well-being, and muscle strength. Together, this shows the multifaceted and organ-specific roles of carnosine peptides and establishes Gadl1 knockout mice as a versatile model to explore carnosine biology and its therapeutic potential.

References

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