Concepedia

Notoginsenoside R1 attenuates sevoflurane-induced neurotoxicity

Yibing Zhang, Yong Zhao, Yongwang Ran, Jian‐You Guo, Haifeng Cui, Sha Liu

Translational Neuroscience · 2020 · 19 citations · 38 references

DOIFull text

Open access

Abstract

This study revealed the neuroprotective effects of NGR1 through effective suppression of apoptosis and ROS via regulation of apoptotic proteins and activation of Nrf2/HO-1 and sestrin 2/AMPK signaling cascades.

References

38

Early Exposure to Common Anesthetic Agents Causes Widespread Neurodegeneration in the Developing Rat Brain and Persistent Learning Deficits

Vesna Jevtović‐Todorović, Richard E. Hartman, Yukitoshi Izumi et al. · Journal of Neuroscience · 2003 · 2K citations · Full text

Transcription Factor Nrf2 Coordinately Regulates a Group of Oxidative Stress-inducible Genes in Macrophages

Tetsuro Ishii, Ken Itoh, Satoru Takahashi et al. · Journal of Biological Chemistry · 2000 · 1.4K citations · Full text

Early Exposure to Anesthesia and Learning Disabilities in a Population-based Birth Cohort

Robert T. Wilder, Randall P. Flick, Juraj Šprung et al. · Anesthesiology · 2009 · 1.4K citations · Full text

Cytosol-to-membrane redistribution of Bax and Bcl-X<sub>L</sub>during apoptosis

Yi‐Te Hsu, Keith G. Wolter, Richard J. Youle · Proceedings of the National Academy of Sciences · 1997 · 1.1K citations · Full text

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Identification of the NF-E2-related Factor-2-dependent Genes Conferring Protection against Oxidative Stress in Primary Cortical Astrocytes Using Oligonucleotide Microarray Analysis

Jong‐Min Lee, Marcus J. Calkins, Kaimin Chan et al. · Journal of Biological Chemistry · 2003 · 782 citations · Full text

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