Synthesis of substituted pyrimidine using <scp>ZnFe₂O₄</scp> nanocatalyst via one pot multi‐component reaction ultrasonic irradiation

Abstract

Abstract A highly efficient, eco‐friendly, recyclable heterogeneous ZnFe 2 O 4 nanocatalyzed synthesis of 2‐amino‐4‐substituted 1,4‐dihydrobenzo[4,5]imidazo[1,2‐a]pyrimidine‐3‐carbonitrile (4a‐j) derivatives via one pot multicomponent reaction of benzimidazole ( 1 ), substituted aromatic aldehyde ( 2a‐j ) and malononitrile ( 3 ) under ultrasonic irradiations. Significance of this synthetic approach is short reaction time, easy handling, simplicity, efficiency, high yield, and recoverable catalyst.