Carl W. Sigel

Synthesis and antitumor activity of 2,4-diamino-6-(2,5-dimethoxybenzyl)-5-methylpyrido[2,3-d]pyrimidine

E. M. GRIVSKY, Shuliang Lee, Carl W. Sigel et al. · Journal of Medicinal Chemistry · 1980 · 359 citations

Medicinal Chemistry, Bioorganic Chemistry, Antitumor Activity +12

Bruceantin, a new potent antileukemic simaroubolide from Brucea antidysenterica

S. Morris Kupchan, Ronald W. Britton, Myra F. Ziegler et al. · The Journal of Organic Chemistry · 1973 · 266 citations

Pharmaceutical Science, Antiparasitic Agent, Immunology +17

Tumor inhibitors. 100. Isolation and structural elucidation of bruceantin and bruceantinol, new potent antileukemic quassinoids from Brucea antidysenterica

S. Morris Kupchan, Ronald W. Britton, John A. Lacadie et al. · The Journal of Organic Chemistry · 1975 · 162 citations

Molecular Pharmacology, Medicinal Chemistry, Pharmaceutical Science +14

Jatrophone, a novel macrocyclic diterpenoid tumor inhibitor from Jatropha gossypiifolia

S. Morris Kupchan, Carl W. Sigel, M Matz et al. · Journal of the American Chemical Society · 1970 · 145 citations

Pharmaceutical Science, Chemoprevention Strategy, Altmetric Attention Score +17

Tumor inhibitors. 111. Structure and stereochemistry of jatrophone, a novel macrocyclic diterpenoid tumor inhibitor

S. Morris Kupchan, Carl W. Sigel, M Matz et al. · Journal of the American Chemical Society · 1976 · 105 citations

Altmetric Attention Score, Pharmacotherapy, Chemical Biology +17