Effect of Increased Lactate Dehydrogenase A Activity and Aerobic Glycolysis on the Proinflammatory Profile of Autoimmune CD8+ T Cells in Rheumatoid Arthritis - Concepedia

Concepedia

Publication | Open Access

Effect of Increased Lactate Dehydrogenase A Activity and Aerobic Glycolysis on the Proinflammatory Profile of Autoimmune CD8+ T Cells in Rheumatoid Arthritis

DOI Full Paper Access

94

Citations

36

References

2020

Year

Margarida Souto‐Carneiro, Karel D. Klika, Mónica Abreu, André P. Meyer, Rainer Saffrich, Roger Sandhoff, Richard Jennemann, Franziska V. Kraus, Lars‐Oliver Tykocinski, Volker Eckstein,

Arthritis & Rheumatology

Abstract

Remodeling glucose and glutamine metabolism in RA CD8+ T cells by targeting LDHA activity can reduce the deleterious inflammatory and cytolytic contributions of these cells to the development of autoimmunity.

References

	Year	Citations

Page 1