Panax notoginseng saponins prevent colitis-associated colorectal cancer development: the role of gut microbiota

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A decrease of the butyrate-producing species <i>Roseburia hominis</i> and <i>Faecalibacterium prausnitzii</i> defines dysbiosis in patients with ulcerative colitis

Kathleen Machiels, Marie Joossens, João Sabino et al. · Gut · 2013 · 1.9K citations

Life Sciences, Immunology, Microbiology +17

Chemically induced mouse models of acute and chronic intestinal inflammation

Stefan Wirtz, Vanessa Popp, Markus Kindermann et al. · Nature Protocols · 2017 · 1.5K citations

Life Sciences, Immunology, Pathology +12

GPR109A Is a G-protein–Coupled Receptor for the Bacterial Fermentation Product Butyrate and Functions as a Tumor Suppressor in Colon

Muthusamy Thangaraju, Gail Cresci, Kebin Liu et al. · Cancer Research · 2009 · 772 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +9

Lipocalin 2 Protects from Inflammation and Tumorigenesis Associated with Gut Microbiota Alterations

Alexander R. Moschen, Romana R. Gerner, Jun Wang et al. · Cell Host & Microbe · 2016 · 401 citations · Full text

Life Sciences, Cancer Biology, Immunology +16