Concepedia

Copper and iron ions accelerate the prion-like propagation of α-synuclein: A vicious cycle in Parkinson's disease

Yang Li, Chen Yang, Shilin Wang, Dong Yang, Yu Zhang, Li Xu, Liang Ma, Jiaojiao Zheng, Robert B. Petersen, Ling Zheng,

International Journal of Biological Macromolecules · 2020 · 70 citations · 60 references

DOI

Concepts

References

60

In vivo demonstration that α-synuclein oligomers are toxic

Beate Winner, Roberto Jappelli, Samir K. Maji et al. · Proceedings of the National Academy of Sciences · 2011 · 1.5K citations · Full text

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Transition Metals, Ferritin, Glutathione, and Ascorbic Acid in Parkinsonian Brains

Peter Riederer, E. Sofić, Wolf‐Dieter Rausch et al. · Journal of Neurochemistry · 1989 · 1.4K citations

, , +11

Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson’s Disease

Sangjune Kim, Seung‐Hwan Kwon, Tae‐In Kam et al. · Neuron · 2019 · 1.4K citations · Full text

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Metal-triggered Structural Transformations, Aggregation, and Fibrillation of Human α-Synuclein

Vladimir N. Uversky, Jie Li, Anthony L. Fink · Journal of Biological Chemistry · 2001 · 1.1K citations · Full text

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Exosomal cell-to-cell transmission of alpha synuclein oligomers

Karin M. Danzer, Lisa R. Kranich, Wolfgang Ruf et al. · Molecular Neurodegeneration · 2012 · 858 citations · Full text

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