Concepedia

Prognostic impacts of tumoral expression and serum levels of PD-L1 and CTLA-4 in colorectal cancer patients

Yusuke Omura, Yuji Toiyama, Yoshinaga Okugawa, Chengzeng Yin, Tsunehiko Shigemori, Kurando Kusunoki, Yukina Kusunoki, Shozo Ide, Tadanobu Shimura, Hiroyuki Fujikawa,

Cancer Immunology Immunotherapy · 2020 · 55 citations · 37 references

Open access

Concepts

MedicineImmunologyOncologyCancer ImmunologyTumor ImmunologyTumor ProgressionCancer BiomarkersCancer ImmunotherapyColorectal CancerImmune Checkpoint InhibitorsImmuno-oncology BiomarkersTumor MarkersColorectal Cancer BiomarkersColorectal Cancer PrognosisCtla-4 SignalingCytotoxic T-lymphocyte-associated Protein 4 InhibitorsPd-l1 BlockadeProgrammed Cell Death Protein 1 (Pd-1) PathwayProgrammed Death-ligand 1 Biomarker

References

37

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

F. Stephen Hodi, Steven O’Day, David F. McDermott et al. · New England Journal of Medicine · 2010 · 15.2K citations · Full text

Medicine, Clinical Sciences, Oncology +12

PD-1 Blockade in Tumors with Mismatch-Repair Deficiency

Dung T. Le, Jennifer N. Uram, Hao Wang et al. · New England Journal of Medicine · 2015 · 9.4K citations · Full text

Life Sciences, Immunology, Oncology +17

<i>K-ras</i> Mutations and Benefit from Cetuximab in Advanced Colorectal Cancer

Christos S. Karapetis, Shirin Khambata‐Ford, Derek J. Jonker et al. · New England Journal of Medicine · 2008 · 3.6K citations

Medicine, Oncology, Pharmacology +17

Colorectal cancer statistics, 2014

Rebecca L. Siegel, Carol DeSantis, Ahmedin Jemal · CA A Cancer Journal for Clinicians · 2014 · 2.6K citations · Full text

Medicine, Oncology, Cancer Epidemiology +16

Cancer Immunotherapy

Jennifer Couzin-Frankel · Science · 2013 · 2K citations

Medicine, Immunology, Oncology +13