Silver(<scp>i</scp>)-catalyzed selective hydroalkoxylation of C2-alkynyl quinazolinones to synthesize quinazolinone-fused eight-membered N,O-heterocycles

Abstract

A silver-catalyzed selective 8-<italic>endo-dig</italic>cyclization of C2-alkynyl quinazolinones was developed to prepare a series of novel quinazolinone-fused eight-membered N,O-heterocycles in good-to-excellent yields under mild reaction conditions.