<p>Highly Efficient Targeting of EGFR-Expressing Tumor Cells with UniCAR T Cells via Target Modules Based on Cetuximab<sup>®</sup></p> - Concepedia

Concepedia

Publication | Open Access

<p>Highly Efficient Targeting of EGFR-Expressing Tumor Cells with UniCAR T Cells via Target Modules Based on Cetuximab<sup>®</sup></p>

DOI Full Paper Access

25

Citations

28

References

2020

Year

Justyna Jureczek, Anja Feldmann, Ralf Bergmann, Claudia Arndt, Nicole Berndt, Stefanie Koristka, Liliana R. Loureiro, Nicola Mitwasi, Anja Hoffmann, Alexandra Kegler,

OncoTargets and Therapy

Abstract

Improved efficiency of the scFv-based TM allowed the redirection of UniCAR T cells towards tumor cells expressing high as well as low EGFR levels in comparison to nb-based αEGFR TMs.

References

	Year	Citations

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