Concepedia

Publication | Open Access

Sirt6 Alleviated Liver Fibrosis by Deacetylating Conserved Lysine 54 on Smad2 in Hepatic Stellate Cells

DOIFull Paper Access

154

Citations

36

References

2020

Year

Jinhang Zhang, Yanping Li, Qinhui Liu, Ya Huang, Rui Li, Tong Wu, Zijing Zhang, Jian Zhou, Hui Huang, Qin Tang,
Hepatology

Abstract

Sirt6 plays a key role in HSC activation and liver fibrosis by deacetylating the profibrogenic transcription factor Smad2. Sirt6 may be a potential therapeutic target for liver fibrosis.

References

YearCitations

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