Concepedia

A multifunctional anti-inflammatory drug that can specifically target activated macrophages, massively deplete intracellular H2O2, and produce large amounts CO for a highly efficient treatment of osteoarthritis

Guangzhen Yang, Mengni Fan, Jingwu Zhu, Ling Chen, Lihuang Wu, Xin Zhang, Ming Zhang, Jiayi Li, Qingqiang Yao, Zhongwei Gu,

Biomaterials · 2020 · 153 citations · 45 references

References

45

Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway

Leo E. Otterbein, Fritz H. Bach, Jawed Alam et al. · Nature Medicine · 2000 · 2.1K citations

Life Sciences, Biochemistry, Immunology +12

Carbon Monoxide-Releasing Molecules

Roberto Motterlini, James Clark, Roberta Foresti et al. · Circulation Research · 2002 · 991 citations

Life Sciences, Pharmacology, Physiology +14

Neutrophil membrane-coated nanoparticles inhibit synovial inflammation and alleviate joint damage in inflammatory arthritis

Qiangzhe Zhang, Diana Dehaini, Yue Zhang et al. · Nature Nanotechnology · 2018 · 947 citations

Medicine, Immunology, Molecular Pharmaceutics +17

Simple Peptide‐Tuned Self‐Assembly of Photosensitizers towards Anticancer Photodynamic Therapy

Kai Liu, Ruirui Xing, Qianli Zou et al. · Angewandte Chemie International Edition · 2016 · 505 citations · Full text

Pharmacy, Pharmaceutics, Pharmacology +17

Carbon monoxide‐releasing molecules (CO‐RMs) attenuate the inflammatory response elicited by lipopolysaccharide in RAW264.7 murine macrophages

Philip Sawle, Roberta Foresti, Brian E. Mann et al. · British Journal of Pharmacology · 2005 · 389 citations · Full text

Life Sciences, Biochemistry, Immunology +17