Desensitizing highly sensitized heart transplant candidates with the combination of belatacept and proteasome inhibition

A Phase III Study of Belatacept‐based Immunosuppression Regimens versus Cyclosporine in Renal Transplant Recipients (BENEFIT Study)

Flavio Vincenti, B Charpentier, Yves Vanrenterghem et al. · American Journal of Transplantation · 2010 · 946 citations

Medicine, Nephrology, Pharmacology +15

Rational Development of LEA29Y (belatacept), a High-Affinity Variant of CTLA4-Ig with Potent Immunosuppressive Properties

Christian P. Larsen, Thomas C. Pearson, Andrew Adams et al. · American Journal of Transplantation · 2005 · 710 citations · Full text

Life Sciences, Immunology, Pharmacology +17

Rituximab and Intravenous Immune Globulin for Desensitization during Renal Transplantation

Ashley Vo, Marina Lukovsky, Mieko Toyoda et al. · New England Journal of Medicine · 2008 · 687 citations

Medicine, Hematology, Kidney Transplantation +2

CD28 activation pathway regulates the production of multiple T-cell-derived lymphokines/cytokines.

Craig B. Thompson, Tullia Lindsten, J A Ledbetter et al. · Proceedings of the National Academy of Sciences · 1989 · 659 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Phase III Study of Belatacept Versus Cyclosporine in Kidney Transplants from Extended Criteria Donors (BENEFIT‐EXT Study)

Antoine Dürrbach, JO Medina Pestana, Thomas C. Pearson et al. · American Journal of Transplantation · 2010 · 565 citations · Full text

Medicine, Nephrology, Pharmacotherapy +17