Human interleukin-4–treated regulatory macrophages promote epithelial wound healing and reduce colitis in a mouse model

Timothy S. Jayme, Gabriella Leung, Arthur Wang, Matthew L. Workentine, Sruthi Rajeev, Adam Shute, Blanca E. Callejas, Nicole L. Mancini, Paul L. Beck, Remo Panaccione,

Science Advances · 2020 · 83 citations · 36 references

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Abstract

mice significantly reduced disease. These findings from in vitro and in vivo analyses provide proof-of-concept support for the development of autologous M(IL4) transfer as a cellular immunotherapy for IBD.

References

36