<p>Comparative Cholinesterase, α-Glucosidase Inhibitory, Antioxidant, Molecular Docking, and Kinetic Studies on Potent Succinimide Derivatives</p>

Ashfaq Ahmad, Farhat Ullah, Abdul Sadiq, Muhammad Ayaz, Muhammad Saeed Jan, Muhammad Shahid, Abdul Wadood, Fawad Mahmood, Umer Rashid, Riaz Ullah,

Drug Design Development and Therapy · 2020 · 37 citations · 42 references

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Abstract

Both succinimide derivatives exhibited considerable inhibitory activities against cholinesterases and α-glucosidase enzymes. Of these two, compound <b>1</b> revealed to be more potent against all the in-vitro targets which was supported by molecular docking with the lowest binding energies. Moreover, compound <b>1</b> also proved to have antiradical properties.

References

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