Concepedia

Publication | Open Access

Transcriptional consequences of MBD5 disruption in mouse brain and CRISPR-derived neurons

DOIFull Paper Access

21

Citations

77

References

2020

Year

Catarina M. Seabra, Tatsiana Aneichyk, Serkan Erdin, Derek J.C. Tai, Celine de Esch, Parisa Razaz, Yu An, Poornima Manavalan, Ashok Ragavendran, Alexei Stortchevoi,
Molecular Autism

Abstract

Our study points to modest and context-dependent transcriptional consequences of Mbd5 disruption in the brain. It also suggests a possible link between MBD5 and perturbations in ciliary function, which is an established pathogenic mechanism in developmental disorders and syndromes.

References

YearCitations

Page 1