Derek J.C. Tai

Engineering microdeletions and microduplications by targeting segmental duplications with CRISPR

Derek J.C. Tai, Ashok Ragavendran, Poornima Manavalan et al. · Nature Neuroscience · 2016 · 96 citations · Full text

Engineering, Segmental Duplications, Genetics +11

SGK1 Phosphorylation of IκB Kinase α and p300 Up-regulates NF-κB Activity and Increases N-Methyl-D-aspartate Receptor NR2A and NR2B Expression

Derek J.C. Tai, Chia-Chen Su, Yun‐Li Ma et al. · Journal of Biological Chemistry · 2008 · 93 citations · Full text

MeCP2 SUMOylation rescues Mecp2-mutant-induced behavioural deficits in a mouse model of Rett syndrome

Derek J.C. Tai, Yen‐Chen Liu, Wei‐Lun Hsu et al. · Nature Communications · 2016 · 71 citations · Full text

Loss of MAGEL2 in Prader-Willi syndrome leads to decreased secretory granule and neuropeptide production

Helen Chen, A. Kaitlyn Victor, Jonathon Klein et al. · JCI Insight · 2020 · 66 citations · Full text

Protein Secretion, Molecular Regulation, Pathology +23

16p11.2 deletion is associated with hyperactivation of human iPSC-derived dopaminergic neuron networks and is rescued by RHOA inhibition in vitro

Maria Sundberg, Hannah Pinson, Richard S. Smith et al. · Nature Communications · 2021 · 61 citations · Full text