Molecular Detection of SARS-CoV-2 Infection in FFPE Samples and Histopathologic Findings in Fatal SARS-CoV-2 Cases

Miroslav Sekulic, Holly Harper, Behtash Ghazi Nezami, Daniel Shen, Simona Pichler Sekulic, Aaron T Koeth, Clifford V. Harding, Hannah Gilmore, Navid Sadri

American Journal of Clinical Pathology · 2020 · 100 citations · 15 references

DOIFull text

Open access

Abstract

SARS-CoV-2 testing and viral sequencing can be performed from FFPE tissue. Detection and sequencing of SARS-CoV-2 in combination with morphological findings from postmortem tissue examination can aid in gaining a better understanding of the virus's pathophysiologic effects on human health.

References

15