In Vitro Biocompatibility Evaluation of Nine Dermal Fillers on L929 Cell Line

Abstract

Data obtained suggest that although examined fillers are not cytotoxic, they show different effects on the <i>in vitro</i> cell proliferation rate. <i>In vitro</i> studies of medical devices could lead to important implications since these could aid to predict effects about their <i>in vivo</i> application. These easy and rapid assays could be useful to test new materials intended for human use avoiding animal tests.