Concepedia

Ivermectin, antiviral properties and COVID-19: a possible new mechanism of action

Emanuele Rizzo

Naunyn-Schmiedeberg s Archives of Pharmacology · 2020 · 110 citations · 24 references

DOIFull text

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Concepts

References

24

The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro

Leon Caly, Julian Druce, Mike Catton et al. · Antiviral Research · 2020 · 2.3K citations · Full text

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Zn2+ Inhibits Coronavirus and Arterivirus RNA Polymerase Activity In Vitro and Zinc Ionophores Block the Replication of These Viruses in Cell Culture

Aartjan J.W. te Velthuis, Sjoerd H. E. van den Worm, Amy Sims et al. · PLoS Pathogens · 2010 · 916 citations · Full text

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Ivermectin is a specific inhibitor of importin α/β-mediated nuclear import able to inhibit replication of HIV-1 and dengue virus

Kylie M. Wagstaff, Haran Sivakumaran, Steven M. Heaton et al. · Biochemical Journal · 2012 · 684 citations · Full text

, , +14

A potential role for integrins in host cell entry by SARS-CoV-2

Christian J A Sigrist, Alan Bridge, Philippe Le Mercier · Antiviral Research · 2020 · 336 citations · Full text

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The broad spectrum antiviral ivermectin targets the host nuclear transport importin α/β1 heterodimer

Sundy N.Y. Yang, Sarah C. Atkinson, Chunxiao Wang et al. · Antiviral Research · 2020 · 329 citations

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