PharmacyPediatricsToxicologyCytogeneticsReproductive ToxicologySubstance Use DisordersBiomarkers Of Genotoxic ExposureDevelopmental GenotoxicityDna DamageDrug ToxicityDrugs Of AbuseChromosomal Abnormalities EpidemiologyChromosome BreakageDrug-induced Dna DamageDrug-induced Prenatal ToxicityNumerical Chromosomal AbnormalitiesPediatric Drug ExposurePregnancy Drug ExposurePrenatal Drug Exposure
An increase of chromosomal abnormalities was found in leukocytes of LSD users compared to drug-free controls. Elevated breakage rates were also found in children exposed to the drug in utero. The data showed no correlation between amount of drug per dose, number of doses, or total dosage and frequency of chromosomal breaks.
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Chromosome Abnormalities in Constitutional Aplastic Anemia
Gerald E. Bloom, Susan Warner, Park S. Gerald et al. · New England Journal of Medicine · 1966 · 245 citations
Life Sciences, Genetics, Hematology +16
LEUKqMIA AND LYMPHOCYTES IN ATAXIA-TELANGIECTASIA
Frederick Hecht · The Lancet · 1966 · 204 citations
Life Sciences, Immunology, Neurology +12
Michael Swift · Annals of Internal Medicine · 1966 · 185 citations
Medicine, Dermatology, Immunology +15