Overcoming barriers to early disease intervention

An Anti-CD3 Antibody, Teplizumab, in Relatives at Risk for Type 1 Diabetes

Kevan C. Herold, Brian N. Bundy, S. Alice Long et al. · New England Journal of Medicine · 2019 · 1K citations · Full text

Effects of Insulin in Relatives of Patients with Type 1 Diabetes Mellitus

New England Journal of Medicine · 2002 · 837 citations

RETRACTED ARTICLE: Rescue of the spinal muscular atrophy phenotype in a mouse model by early postnatal delivery of SMN

Kevin D. Foust, Xueyong Wang, Vicki L. McGovern et al. · Nature Biotechnology · 2010 · 685 citations · Full text

Knockout Mouse, Early Postnatal Delivery, Spinal Cord Injury +8

Randomized Trial of Verubecestat for Prodromal Alzheimer’s Disease

Michael Egan, James Kost, Tiffini Voss et al. · New England Journal of Medicine · 2019 · 535 citations · Full text

Treatment With Carfilzomib-Lenalidomide-Dexamethasone With Lenalidomide Extension in Patients With Smoldering or Newly Diagnosed Multiple Myeloma

Neha Korde, Mark Roschewski, Adriana Zingone et al. · JAMA Oncology · 2015 · 308 citations · Full text