Skin‐infiltrating basophils promote atopic dermatitis‐like inflammation via IL‐4 production in mice

Abstract

Skin-infiltrating basophils promoted OX-induced AD-like skin inflammation through their local production of IL-4, rather than the induction of Th2 cell differentiation in draining LNs. This study suggests that the selective targeting of basophils could be a beneficial strategy in the treatment of a certain type of AD.