Entropy · 2020 · 157 citations · 29 references
ComputingComputer ScienceRadiologyDiagnostic ImagingDiagnostic RadiologyMachine LearningComputed TomographyComputer-aided DiagnosisDeep LearningFeature ExtractionMedical Image AnalysisMedical ImagingAccuracyDeep Learning DiagnosticsDeep Learning In RadiologyDeep Learning-based ClassificationDeep Learning-based DetectionDeep Learning-based DiagnosisLong Short-term Memory NetworksThresholding
COVID‑19 has overwhelmed global health systems by straining limited capacity amid a surge of suspected cases. The study aims to develop a rapid, accurate diagnostic method to relieve radiologists from the burden of suspected COVID‑19 cases. The authors extract deep‑learning and Q‑deformed entropy features from pre‑processed CT lung scans, isolate the background via histogram thresholding, and classify the combined feature set with an LSTM network. The integrated feature approach yields a 99.68 % accuracy in distinguishing COVID‑19, pneumonia, and healthy lungs among 321 patients.
Many health systems over the world have collapsed due to limited capacity and a dramatic increase of suspected COVID-19 cases. What has emerged is the need for finding an efficient, quick and accurate method to mitigate the overloading of radiologists’ efforts to diagnose the suspected cases. This study presents the combination of deep learning of extracted features with the Q-deformed entropy handcrafted features for discriminating between COVID-19 coronavirus, pneumonia and healthy computed tomography (CT) lung scans. In this study, pre-processing is used to reduce the effect of intensity variations between CT slices. Then histogram thresholding is used to isolate the background of the CT lung scan. Each CT lung scan undergoes a feature extraction which involves deep learning and a Q-deformed entropy algorithm. The obtained features are classified using a long short-term memory (LSTM) neural network classifier. Subsequently, combining all extracted features significantly improves the performance of the LSTM network to precisely discriminate between COVID-19, pneumonia and healthy cases. The maximum achieved accuracy for classifying the collected dataset comprising 321 patients is 99.68%.
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