Concepedia

Publication | Open Access

Cardiac Overexpression of PDE4B Blunts β-Adrenergic Response and Maladaptive Remodeling in Heart Failure

DOIFull Paper Access

77

Citations

44

References

2020

Year

Sarah Arangurem Karam, Jean Piero Margaria, Aurélia Bourcier, Delphine Mika, Audrey Varin, Ibrahim Bedioune, Marta Lindner, Kaouter Bouadjel, Matthieu Dessillons, Françoise Gaudin,
Circulation

Abstract

Our results indicate that a moderate increase in PDE4B is cardioprotective and suggest that cardiac gene therapy with PDE4B might constitute a new promising approach to treat heart failure.

References

YearCitations

Page 1